Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
Genome stability during DNA replication depends on a coordinated network of enzymatic activities that ensure accurate duplication and mitigate threats arising from DNA lesions, replication impediments ...
Bacterial DNA replication is a highly coordinated process that ensures faithful genome duplication and cell division. Replication initiates at a single chromosomal origin (oriC) where multiple copies ...